Organofluoride compounds have become one of the most important and common class of substances among…

Abstract The halogenation of organic substrates is one the most important transformations in organic synthesis.…

We selected two reactions to assess the ability of the CSTR cascade to handle the…

The scheme of the setup for continuous handling of solid-forming reactions in the CSTR cascade…

The RTD profiles of the CSTR cascade were obtained using the pulse injection method (Fig.…

Materials Reagents and chemicals used in this work, including methylene blue, isoprene, maleic acid anhydride,…

Abstract Continuous handling of solids creates challenges for realizing continuous production of pharmaceuticals and fine…

For the difluoromethylation reaction, the inlets A, B and D were attached with standard connectors…

For the SLM process, the 3D CAD model is dissected by the process software into…

To accomplish the desired difluoromethylation reaction, three inlets for substrate, nBuLi and CHF3 are required (Fig. 2 and 3).…