Posted inGeneral Concepts
Halogenation of organic compounds using continuous flow and microreactor technology
Abstract The halogenation of organic substrates is one the most important transformations in organic synthesis.…
Posted inGeneral Concepts
Continuous handling of reactions forming solids
We selected two reactions to assess the ability of the CSTR cascade to handle the…
Posted inGeneral Concepts
General procedure for solid-forming reactions in the CSTR cascade
The scheme of the setup for continuous handling of solid-forming reactions in the CSTR cascade…
Posted inGeneral Concepts
Residence time distribution (RTD) characterization
The RTD profiles of the CSTR cascade were obtained using the pulse injection method (Fig.…
Posted inGeneral Concepts
Experimental section
Materials Reagents and chemicals used in this work, including methylene blue, isoprene, maleic acid anhydride,…
Posted inGeneral Concepts
A miniature CSTR cascade for continuous flow of reactions containing solids
Abstract Continuous handling of solids creates challenges for realizing continuous production of pharmaceuticals and fine…
Posted inGeneral Concepts
Chemistry
For the difluoromethylation reaction, the inlets A, B and D were attached with standard connectors…
Posted inGeneral Concepts
Reactor printing and characterization
For the SLM process, the 3D CAD model is dissected by the process software into…
Posted inGeneral Concepts
Reactor design
To accomplish the desired difluoromethylation reaction, three inlets for substrate, nBuLi and CHF3 are required (Fig. 2 and 3).…
Posted inGeneral Concepts
Design and 3D printing of a stainless steel reactor for continuous difluoro methylations using fluoroform
Abstract Herein we present a continuous flow reactor printed from stainless steel by selective laser…